ODCs

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1 OMIM reference -
1 associated gene
6 signs/symptoms

COMMON GENES: 1
PROTEIN INTERACTIONS: 1
COMMON SIGNS: 1

3 OMIM references -
3 associated genes
4 signs/symptoms

Woolly hair-palmoplantar keratoderma-dilated cardiomyopathy syndrome

Keratosis palmoplantaris striata


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	DSP	(0.78)	KRT1

Citations in the biomedical literature:

Woolly hair-palmoplantar keratoderma-dilated cardiomyopathy syndrome		Keratosis palmoplantaris striata
	Synonym(s): - Carvajal syndrome - Woolly hair-palmoplantar hyperkeratosis-dilated cardiomyopathy syndrome - Wooly hair - palmoplantar keratoderma - dilated cardiomyopathy - Wooly hair-palmoplantar hyperkeratosis-dilated cardiomyopathy syndrome		Synonym(s): - Keratosis palmoplantaris striata et areata - Keratosis palmoplantaris varians of Wachters - Striate palmoplantar keratoderma

	Classification (Orphanet): - Rare cardiac disease - Rare genetic disease - Rare skin disease		Classification (Orphanet): - Rare genetic disease - Rare skin disease

	Classification (ICD10): (no data available)		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: - Average age onset: - Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 3 OMIM references - No MeSH references


COMMON SIGNS	- Palmoplantar hyperkeratosis / keratoderma

Woolly hair-palmoplantar keratoderma-dilated cardiomyopathy syndrome		Keratosis palmoplantaris striata
	Very frequent - Autosomal recessive inheritance - Cardiomyopathy / hypertrophic / dilated - Woolly / frizzy hair Occasional - Heart / cardiac failure - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment		Very frequent - Autosomal dominant inheritance Frequent - Hair and scalp anomalies - Nails anomalies